The paper considers the problem of forecasting of hydrocarbon production in regions with a low degree of exploration. A forecast algorithm allowing for simulation of production dynamics at oilfields is proposed. The algorithm is part of a comprehensive methodological approach to the geological and economic assessment of promising petroleum territories - IPGG-Estimator, developed at IPGG SB RAS. The developed software allows for forecasting key parameters of the development of various oil and gas facilities. Approbation of the algorithm was performed on the Eastern Siberia and the Far East. The region is characterized by the presence of significant oil and gas resources and a low degree of their exploration, which creates the conditions for the start of large-scale production. Currently large-scale natural gas production in Eastern Siberia is constrained by the lack of a gas transportation infrastructure, however PAO Gazprom completes the construction of the Siberia Power pipeline in late 2019. Structure and quality of the region's resource base have a significant influence on the dynamics of gas production. The natural gas of Eastern Siberia has complex composition and contains a large number of homologs of methane (ethane, propane, butane, helium, etc.). Development of processing facilities will result in high added value products, that will allow for realization of the economic and geopolitical interests of the country, increase in the socio-economic level of the development of the regions. Recommendations for state regulation of the gas industry in Siberia were proposed.