In modern conditions of geopolitical instability, the problem of developing regional space to strengthen territorial integrity and ensure energy security is becoming increasingly important. The organization of mineral resource centers (MRC) is one of the effective forms of spatial development, especially for the regions of the Arctic zone. MRC contribute to solving the problems of integrated development of energy resources and the formation of a transport and logistics framework for poorly studied territories, which governs the effective advancement of the regional economy. The article systematizes the theoretical foundations for the development of MRC and updates the prerequisites for their formation in the Arctic. A conceptual scheme of territorial development is proposed with the allocation of the Arctic MRC in the north of the Krasnoyarsk Krai, a financial and economic model is built, an assessment of the main production and technical indicators is made, and the criteria for investment attractiveness are calculated. It is shown that the expediency of organizing the Arctic MRC is defined primarily by the strategic goals and objectives of the development of the Arctic zone at the federal level, and economic efficiency - by the development of a multi-level transport and logistics infrastructure. At the same time, despite large-scale capital investments and their long payback, the authors substantiate feasibility of developing the Arctic MRC through a high multiplier effect and propose a system for its assessment on the national, regional and corporate scales.