We present results of lithological and geochemical studies of Paleozoic deposits stripped by drilling within the Ledyanskaya area in the north of the Tunguska syneclise. The studied section has a terrigenous sulfate-carbonate composition and is complicated by trap intrusions. We have established that the Ordovician-Devonian sedimentation proceeded within an epicontinental basin, with its depth varying from supralittoral to lower sublittoral zones. In the Carboniferous and Permian, coastal-continental sedimentation was predominant; in the Late Permian it was accompanied by volcanic activity. Analysis of the poroperm properties of rocks has distinguished three potential oil reservoirs: Silurian reef carbonate deposits and Ordovician and Carboniferous sand horizons. The Lower Silurian argillaceous-carbonate rocks and Devonian carbonate-sulfate-clay members, halite beds, dolerite bodies, and tuffaceous rocks are probably confining beds of these reservoirs. Geochemical study of organic matter has shown several possible sources of hydrocarbons: Upper Proterozoic deposits, Lower and Middle Cambrian Kuonamka complex, Middle Devonian Yukta Formation, and Upper Paleozoic coal-bearing deposits.